1. Scope

1.1 This test method describes the determination of 2,4-toluene diisocyanate (2,4-TDI) and 2,6-toluene diisocyanate (2,6-TDI) in air samples collected from workplace atmospheres in a cassette containing a glass-fiber filter impregnated with 1-(2-pyridyl)piperazine (1-2 PP). This procedure is very effective for determining the vapor content of atmospheres. Atmospheres containing aerosols may produce low results.

1.2 This test method uses a high-performance liquid chromatograph (HPLC) equipped with a fluorescence or an ultraviolet (UV) detector (1-4).

1.3 The validated range of the test method, as written, is from 1.4 to 5.6 [mu]g of 2,4-TDI and 2,6-TDI which is equivalent to approximately 9.8 to 39 ppb for 2,4-TDI and 2,6-TDI based on a 20-L air sample. The HPLC method using an UV detector is capable of detecting 0.078 [mu]g of 2,4-TDI and 0.068 [mu]g of 2,6-TDI in a 4.0-mL solvent volume, which is equivalent to 0.55 ppb for 2,4-TDI and 0.48 ppb for 2,6-TDI based on a 20-L air sample.

1.4 The isomers of 2,4-TDI, and 2,6-TDI, can be separated utilizing a reversed phase column for the HPLC method. Because industrial applications employ an isomeric mixture of 2,4- and 2,6-TDI, the ability to achieve this separation is important.

1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. See Section 9 for specific precautions.

2. Referenced Documents (purchase separately) The documents listed below are referenced within the subject standard but are not provided as part of the standard.

ASTM Standards

D1193 Specification for Reagent Water

D1356 Terminology Relating to Sampling and Analysis of Atmospheres

D1357 Practice for Planning the Sampling of the Ambient Atmosphere

D3686 Practice for Sampling Atmospheres to Collect Organic Compound Vapors (Activated Charcoal Tube Adsorption Method)

E691 Practice for Conducting an Interlaboratory Study to Determine the Precision of a Test Method

Keywords

2,4-toluene diisocyanate; 2,6-toluene diisocyanate;1-(2-Pyridyl)piperazine; 2,4-TDI; 2,6-TDI; air monitoring; high-performance liquid chromatography; sampling and analysis; workplace atmospheres ;

ICS Code

ICS Number Code 13.040.30 (Workplace atmospheres)

DOI: 10.1520/D5836-95

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