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  • BSI
    20/30404078 DC BS EN 16274. Method for Analysis of Allergens. Quantification of an extended list of 57 suspected allergens in ready to inject fragrance materials by gas chromatography mass spectrometry
    Edition: 2020
    $44.66
    / user per year

Description of 20/30404078 DC 2020

The present method permits the identification and quantification of the volatile compounds suspected as allergens, which are present in the fragrance compounds and raw materials used in cosmetic products. The analysis is performed by gas chromatography and mass spectrometry (GC-MS) on matrix samples which are “ready to be injected” and which are compatible with gas chromatography.

The analytes covered by this procedure are based on the contents of Tables 13.1 and 13.2 in the SCCS 1459/11 opinion document (1) and as listed in the legislation proposed by the European Commission. The rationale behind the final choice of procedure analytes is given in the table found in Annex J.

The method was validated at IFRA and CEN level with two solvents, namely methyl pivalate and tert-methyl butyl ether.

Many of the Allergens in the SCCS ‘Opinion’ documentation submitted to the EU Commission consist of multiple isomers of the same molecules and/or complex mixtures.

In many cases, this complexity can be resolved by this Procedure but that leaves a number of target analytes where this isn’t the case.

In addition, the SCCS Opinion also documents a number of CAS Numbers related to the same parent molecule. These are related to the optically active forms of the similar parent structure. For this procedure, the optically active forms are not considered as these require special (and in some cases, very different) GC phases to achieve the required separation.



Standard Number20/30404078 DC
TitleBS EN 16274. Method for Analysis of Allergens. Quantification of an extended list of 57 suspected allergens in ready to inject fragrance materials by gas chromatography mass spectrometry
StatusDefinitive
Publication Date2020-02-24
Identical National Standard OfprEN 16274
DescriptorsPerfumes, Biochemical methods of analysis, Food testing, Food products, Allergies
ICS71.100.60 Essential oils
CommitteeCW/217
PublisherBSI
Pages71

About BSI

BSI Group, also known as the British Standards Institution is the national standards body of the United Kingdom. BSI produces technical standards on a wide range of products and services and also supplies certification and standards-related services to businesses.
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